Entourage Effect: What Does It Mean and How Do You Get It?

When we think about the cannabis plant, we often associate it with CBD (cannabidiol) and THC compounds (tetrahydrocannabinol), but there’s more to cannabis than these two compounds. The cannabis plant contains a wealth of other components that give it its celebrated qualities and versatile uses. So before we dig deep into the question of “what is the entourage effect?”, we need to first establish that this plant contains different components that all function differently. With this in mind, let’s take a look at what the entourage effect is and how it works in the following points.

What is the Entourage Effect?

The cannabis plant contains over 80 cannabinoids and more than 100 turbines that synergize together in order to create a healing effect. This synergy is believed to unleash the whole “healing power” of cannabis. So, instead of inducing the effect of only one component, this should elicit the full effect of the plant and allow the user to garner all its benefits. As explained by the cannabinoid and terpene specialists over at https://thefirefly.com/blogs/culture/cannabis-entourage-effect, these different components work together in a series of reactions between components like CBD and the THC. While the CBD is notorious for its “high” effect, it can counteract the stress-inducing and intoxicating effect of THC and vice versa.

Terpenes also have anti-inflammatory properties and are capable of relieving stress, but while all these effects of different components are proven true, there is still little to no research done on the entourage effect to verify it. But accounts of different people who have experienced the full effect of the cannabis flower indicate that utilizing the cannabis full effect can work better than using its components separately, like using CBD and THC in pure form. Some people have stated that it can work as well as medicine.

Research Perspective

There isn’t much research to show the truth about the entourage effect, but there was some research on the therapeutic effects of using a combination of the cannabis flower components, like using phytocannabinoids in conjunction with terpenes, which can alleviate conditions like anxiety, epilepsy, inflammation, and cancer. There has also been some research done on terpenes and flavonoids, which has showcased that these compounds can work together to produce anti-inflammatory and neuroprotective effects. In addition to this, experiments done on both humans and rats have detailed that CBD can ward off the side effects of THC that many people experience, so using them in conjunction would be more beneficial. Some research also suggests that CBD has an anti-psychoactive effect, which explains why it is effective against counteracting THC psychoactive effects.

How Do You Get It

Unfortunately, the entourage effect hasn’t been subjected to experimentation yet, but since patients react differently to a fixed THC and CBD ratio, there is no fixed formula that can work for everyone. Thus, using Cannabis to get the entourage effect on your part will be purely experimental, since there’s no way of telling what the results will be. You can also ask your healthcare provider about the possible effects since they will have better insight as to how much you can use, especially if you’re taking other medication. Some people who claim that they have experienced the entourage effect, however, have used the full-spectrum CBD oil. So, you might want to try this one out if you want to experience the entourage effect.

More Research is Needed

Medical cannabis is still a new field in medicine, and although there are multiple medical uses for terpenes, CBD, and THC, they were all used separately and not in a full-plant cannabis form. There is some research to support the entourage effect, but they were only conducted at a minimum of two compounds and not all the compounds of the plant, which is essential to prove the existence of the entourage effect. The healing and therapeutic effects of medications using cannabis components, however, promise a better future for medical cannabis, and it might even prove the entourage effect to be true at some point, but until then, using cannabis components separately and with medical advice is the safest way to go.


Now that you know all about the entourage effect from a theoretical point of view, it should be noted that while this effect is real, it is not approved from a medical perspective as more research is yet to be made. In any case, because medical cannabis is still expanding, we can be positive that future prospects about the entourage effect might come to light.